Antidepressants (2026) Why You Feel Worse Before Better

Antidepressants Why You Feel Worse Before Better

Antidepressants can make you feel worse before better because your brain chemistry shifts within hours of your first dose, but serotonin receptors take 4 to 6 weeks to fully adapt. During that gap, side effects like heightened anxiety, nausea, insomnia, and restlessness can mimic or intensify depressive symptoms before the medication’s benefits kick in. If … Read more